Enzymatic amide bond formation: synthesis of aminooxo-acids through a <i>Mycobacterium smegmatis</i> acyltransferase
نویسندگان
چکیده
Starting from anilines and anhydrides a range of aminooxo-acids were prepared with excellent yields reaction times using an acyltransferase M. smegmatis (MsAcT) in water. Applying this process key intermediate SAHA was synthesized.
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ژورنال
عنوان ژورنال: Green Chemistry
سال: 2022
ISSN: ['1463-9262', '1463-9270']
DOI: https://doi.org/10.1039/d2gc00655c